Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14909856 | 0.87 | KDM4E (0.52) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30674020 | 0.84 | NQO2 (0.53) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3344053 | 0.84 | NQO2 (0.53) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL21241466 | 0.83 | PSMD14 (0.53) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5259486 | 0.79 | RAB9A (0.60) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8135776 | 0.78 | LMNA (0.47) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20521768 | 0.78 | NPC1 (0.54) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL23994518 | 0.78 | KDM4E (0.43) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14909268 | 0.78 | NPC1 (0.51) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30224194 | 0.78 | KDM4E (0.43) | KDM4ELMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081789-A2 | HISTONE DEMETHYLASE INHIBITORS FOR TREATING CANCERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2020257733-A1 | HISTONE DEMETHYLASE INHIBITORS FOR TREATING CANCERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-12-24 | — | — | WO | disclosed |