Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707617 | 0.85 | MAPT (0.57) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL1101341 | 0.84 | MAPT (0.69) | RAB9ALMNANPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9052047 | 0.83 | MAPT (0.67) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL2485359 | 0.83 | RAB9A (0.75) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL1101347 | 0.81 | MAPT (0.68) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL8135776 | 0.81 | LMNA (0.47) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL30614510 | 0.81 | MEN1 (0.68) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL170428 | 0.81 | MEN1 (0.68) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL21241466 | 0.80 | PSMD14 (0.53) | RAB9ALMNANPC1MEN1KMT2A | |
| SCHEMBL9057120 | 0.80 | LMNA (0.55) | RAB9ALMNANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824869-A1 | MACROLONE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006050941-A1 | MACROLONE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-05-18 | — | — | WO | disclosed |
| EP-0670315-A1 | Triazole oxime derivatives having antimycotic acitivity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-06 | — | — | EP | disclosed |
| EP-0284203-A2 | Erythromycin derivatives, process for their preparation and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1988-09-28 | — | — | EP | disclosed |