Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484647 | 0.81 | AR (0.51) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL28091070 | 0.72 | NCF1 (0.46) | MAPTTP53ALDH1A1LMNANCF1 | |
| SCHEMBL15871966 | 0.71 | MAPT (0.49) | MAPTTP53ALDH1A1MCOLN3KMT2A | |
| SCHEMBL13326993 | 0.71 | MEN1 (0.47) | MAPTTP53ALDH1A1MCOLN3KMT2A | |
| SCHEMBL27536083 | 0.71 | ALDH1A1 (0.47) | MAPTTP53ALDH1A1MCOLN3KMT2A | |
| SCHEMBL15831876 | 0.70 | NCF1 (0.46) | MAPTTP53ALDH1A1MCOLN3KMT2A | |
| SCHEMBL15831848 | 0.70 | NCF1 (0.46) | MAPTTP53ALDH1A1MCOLN3KMT2A | |
| SCHEMBL16793166 | 0.70 | NCF1 (0.46) | MAPTTP53ALDH1A1MCOLN3KMT2A | |
| SCHEMBL4885809 | 0.70 | MAPT (0.68) | MAPTTP53ALDH1A1MCOLN3KMT2A | |
| SCHEMBL19203563 | 0.69 | ALDH1A1 (0.46) | MAPTTP53ALDH1A1MCOLN3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |