Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.61 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832991 | 0.98 | ALDH1A1 (0.65) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL22839748 | 0.94 | ALDH1A1 (0.60) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL14504494 | 0.89 | ALDH1A1 (0.61) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL15872025 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL16727174 | 0.83 | SLC18A3 (0.55) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL24123854 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL7931333 | 0.82 | HTR3A (0.61) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL2092264 | 0.82 | MAPT (0.50) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL19439047 | 0.82 | ALDH1A1 (1.00) | MAPTALDH1A1MCOLN3MEN1KMT2A | |
| SCHEMBL29370460 | 0.82 | ALDH1A1 (1.00) | MAPTALDH1A1MCOLN3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126840-A1 | ARYL PIPERIDINES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |
| US-10669473-B2 | Organic molecules for use in optoelectronic components | CYNORA GMBH (DE) | 2020-06-02 | — | — | US | disclosed |
| US-20110201608-A1 | SUBSTITUTED NAPHTHYRIDINES AND USE THEREOF AS MEDICINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
| US-7671058-B2 | N-(3,4-disubstituted phenyl) salicylamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-03-02 | — | — | US | disclosed |
| US-7671058-B2 | N-(3,4-disubstituted phenyl) salicylamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20080227784-A1 | N-(3,4-disubstituted phenyl) salicylamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20080227784-A1 | N-(3,4-disubstituted phenyl) salicylamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| WO-2008004127-A2 | METHOD FOR ADMINISTERING TOLPERISONE | SANOCHEMIA PHARMAZEUTIKA AG (US) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201608-A1 | SUBSTITUTED NAPHTHYRIDINES AND USE THEREOF AS MEDICINES | NR4A1, NR4A3, NR0B1 | MAPT 4405/4885ALDH1A1 1585/4885MCOLN3 1197/4885 |
| US-20080227784-A1 | N-(3,4-disubstituted phenyl) salicylamide derivatives | STAT6, RELA, NFKB2 | MAPT 4713/4885ALDH1A1 2263/4885MCOLN3 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.