Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368471 | 0.77 | PKM (0.47) | PPARDAAK1ALOX15HSD17B10 | |
| SCHEMBL31474262 | 0.76 | LMNA (0.49) | HMGCRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL26751660 | 0.73 | ALDH1A1 (0.34) | LMNAALDH1A1KMT2AMAPTAR | |
| SCHEMBL29367635 | 0.71 | PTGDR2 (0.49) | PPARDAAK1ALOX15HSD17B10 | |
| SCHEMBL26968155 | 0.69 | LMNA (0.47) | HMGCRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL28676311 | 0.68 | AAK1 (0.37) | AAK1HSD17B10 | |
| SCHEMBL29602064 | 0.68 | AAK1 (0.37) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22823913 | 0.68 | AAK1 (0.37) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL31437985 | 0.68 | PTGDR (0.40) | HMGCRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL22823750 | 0.68 | AAK1 (0.34) | MAPTAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254559-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2020-12-24 | — | — | WO | disclosed |