Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HMGCR | P04035 | 2/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26968155 | 0.79 | LMNA (0.47) | LMNAALDH1A1MAPTHMGCRMEN1 | |
| SCHEMBL2945856 | 0.79 | ALDH1A1 (0.58) | LMNAALDH1A1MAPTHMGCRMEN1 | |
| SCHEMBL5007334 | 0.76 | PKM (0.69) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4517198 | 0.76 | PKM (0.53) | LMNAALDH1A1MAPTHMGCRMEN1 | |
| SCHEMBL25289926 | 0.76 | PTGS2 (0.49) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31150276 | 0.76 | PTGS2 (0.49) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL22823751 | 0.76 | HMGCR (0.41) | LMNAALDH1A1MAPTHMGCRAAK1 | |
| SCHEMBL31437985 | 0.76 | PTGDR (0.40) | LMNAALDH1A1MAPTHMGCRMEN1 | |
| SCHEMBL19782976 | 0.75 | LMNA (0.40) | LMNAALDH1A1MAPTHMGCRMEN1 | |
| SCHEMBL13104128 | 0.74 | LMNA (0.53) | LMNAALDH1A1MAPTHMGCRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |