Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828122 | 0.90 | CHRNB2 (0.44) | ALDH1A1SMN1; SMN2RAB9ATDP1CHRNB2 | |
| SCHEMBL22828125 | 0.87 | CHRNB2 (0.40) | ALDH1A1SMN1; SMN2RAB9AMAPTCHRNB2 | |
| SCHEMBL22828282 | 0.86 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL22828319 | 0.85 | PTGS2 (0.40) | ALDH1A1SMN1; SMN2RAB9AKMT2ACHRNB2 | |
| SCHEMBL22828313 | 0.82 | L3MBTL1 (0.45) | ALDH1A1MAPTKMT2AMDM2 | |
| SCHEMBL22828141 | 0.81 | CHRNB2 (0.40) | ALDH1A1SMN1; SMN2RAB9ATDP1KMT2A | |
| SCHEMBL6555981 | 0.80 | CNR2 (0.40) | ALDH1A1SMN1; SMN2TDP1MAPTLMNA | |
| SCHEMBL6555980 | 0.80 | CNR2 (0.40) | ALDH1A1SMN1; SMN2TDP1MAPTLMNA | |
| SCHEMBL22828309 | 0.79 | MAPT (0.40) | ALDH1A1SMN1; SMN2RAB9AMAPTKMT2A | |
| SCHEMBL29577072 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RAB9ATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377420-B2 | Compositions and methods for making donor-acceptor azetines | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200399214-A1 | COMPOSITIONS AND METHODS FOR MAKING DONOR-ACCEPTOR AZETINES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377420-B2 | Compositions and methods for making donor-acceptor azetines | AZI2, AAAS, ZRANB2 | ALDH1A1 140/4885SMN1; SMN2 752/4885RAB9A 1036/4885 |
| US-20200399214-A1 | COMPOSITIONS AND METHODS FOR MAKING DONOR-ACCEPTOR AZETINES | AZI2, AAAS, ZRANB2 | ALDH1A1 140/4885SMN1; SMN2 752/4885RAB9A 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.