Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561864 | 1.00 | PTGS2 (0.51) | PTGS2SLC6A4SLC6A2HRH1TP53 | |
| SCHEMBL27151560 | 0.93 | FABP4 (0.51) | PTGS2FABP4FABP5HDAC1HDAC6 | |
| SCHEMBL118053 | 0.92 | PTGS2 (0.59) | PTGS2SLC6A4SLC6A2HRH1TP53 | |
| SCHEMBL9484194 | 0.88 | FABP4 (0.51) | FABP4FABP5HDAC1HDAC6FNTA | |
| SCHEMBL29657620 | 0.85 | PTGS2 (0.50) | PTGS2ALDH1A1FABP4FABP5HDAC1 | |
| SCHEMBL957686 | 0.85 | PTGS2 (0.50) | PTGS2ALDH1A1FABP4FABP5HDAC1 | |
| SCHEMBL13223756 | 0.82 | PTGS2 (0.57) | PTGS2SLC6A4SLC6A2HRH1TP53 | |
| SCHEMBL24427159 | 0.81 | HRH3 (0.40) | ALDH1A1FABP4FABP5SYKPOLB | |
| SCHEMBL10039836 | 0.78 | ALDH1A1 (0.41) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL30887180 | 0.78 | ALDH1A1 (0.41) | ALDH1A1POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20230117655-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2023-04-20 | — | — | US | disclosed |
| US-20230117655-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2023-04-20 | — | — | US | disclosed |
| EP-3990431-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2020-12-31 | — | — | US | disclosed |
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2020-12-31 | — | — | US | disclosed |
| WO-2020261021-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020261021-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | ERCC4, ERCC1, F12 | PTGS2 1209/4885SLC6A4 2966/4885SLC6A2 3711/4885 |
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | ERCC1, OGG1, ERCC4 | PTGS2 241/4885SLC6A4 566/4885SLC6A2 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.