Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184256 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2HRH1ALDH1A1GLA | |
| SCHEMBL31124810 | 0.89 | ALDH1A1 (0.60) | SLC6A4SLC6A2HRH1ALDH1A1GLA | |
| SCHEMBL31739357 | 0.88 | FABP4 (0.61) | FABP4FABP5HDAC1HDAC6MEN1 | |
| SCHEMBL8204008 | 0.88 | FABP4 (0.61) | FABP4FABP5HDAC1HDAC6MEN1 | |
| SCHEMBL2873004 | 0.82 | FABP4 (0.62) | FABP4FABP5HDAC1HDAC6MEN1 | |
| SCHEMBL15835242 | 0.81 | SLC6A4 (0.56) | SLC6A4SLC6A2HRH1ALDH1A1GLA | |
| SCHEMBL10730998 | 0.81 | PGR (0.70) | SLC6A4SLC6A2HRH1ALDH1A1GLA | |
| SCHEMBL24398894 | 0.81 | FABP4 (0.61) | FABP4FABP5HDAC1HDAC6MEN1 | |
| SCHEMBL3066305 | 0.81 | FABP4 (0.61) | FABP4FABP5HDAC1HDAC6MEN1 | |
| SCHEMBL30622271 | 0.81 | FABP4 (0.61) | FABP4FABP5HDAC1HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20230117655-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2023-04-20 | — | — | US | disclosed |
| EP-3990431-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-112449635-A | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | 强生视力健公司 | 2021-03-05 | — | — | CN | disclosed |
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2020-12-31 | — | — | US | disclosed |
| WO-2020260684-A1 | AN OPTICAL SENSOR | Københavns Universitet (DK) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020261021-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | ERCC4, ERCC1, F12 | SLC6A4 2966/4885SLC6A2 3711/4885HRH1 289/4885 |
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | ERCC1, OGG1, ERCC4 | SLC6A4 566/4885SLC6A2 1480/4885HRH1 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.