Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 7/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229992 | 0.87 | HTR2C (0.61) | CA1CA2CA9CA12HDAC3 | |
| SCHEMBL15711291 | 0.81 | CA12 (0.70) | CA1CA2CA9CA12HDAC3 | |
| SCHEMBL6985107 | 0.80 | LMNA (0.67) | CA1CA2CA9CA12PKM | |
| SCHEMBL6982218 | 0.80 | PKM (0.56) | CA1CA2CA9CA12PKM | |
| SCHEMBL6986758 | 0.80 | PKM (0.56) | CA1CA2CA9CA12PKM | |
| SCHEMBL6985319 | 0.80 | CA12 (0.53) | CA1CA2CA9CA12HDAC3 | |
| SCHEMBL6976538 | 0.79 | PKM (0.65) | CA1CA2CA9CA12PKM | |
| SCHEMBL6984820 | 0.79 | HTR6 (0.61) | CA1CA2CA9CA12PKM | |
| SCHEMBL15907913 | 0.78 | CA12 (0.66) | CA1CA2CA9CA12HDAC3 | |
| SCHEMBL31681377 | 0.78 | EIF2AK2 (0.54) | CA1CA2CA9CA12PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005759-A1 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 | NORTH CAROLINA STATE UNIVERSITY | 2013-01-03 | — | — | US | claimed |
| US-20140213632-A1 | HCV Combination Therapy | STELLA APS (DK) | 2014-07-31 | — | — | US | disclosed |
| US-20140127159-A1 | HCV Combination Therapy | STELLA APS (DK) | 2014-05-08 | — | — | US | disclosed |
| US-20130005759-A1 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 | NORTH CAROLINA STATE UNIVERSITY | 2013-01-03 | — | — | US | disclosed |
| US-20130005759-A1 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 | NORTH CAROLINA STATE UNIVERSITY | 2013-01-03 | — | — | US | disclosed |
| WO-2011091209-A1 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011091209-A1 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127159-A1 | HCV Combination Therapy | HAVCR2, EIF2AK2, TIMP3 | CA1 4596/4885CA2 3993/4885CA9 4213/4885 |
| US-20140213632-A1 | HCV Combination Therapy | HAVCR2, EIF2AK2, ZC3HAV1 | CA1 4830/4885CA2 4519/4885CA9 4706/4885 |
| US-20130005759-A1 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 | HAVCR2, CCAR2, EIF2AK2 | CA1 4552/4885CA2 4603/4885CA9 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.