Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22929 | 1.00 | — | — | |
| SCHEMBL43455 | 0.92 | ESR2 (0.47) | POLBESR2SLC18A3SIGMAR1ESR1 | |
| SCHEMBL21538 | 0.92 | ESR2 (0.42) | POLBESR2SLC18A3ESR1CYP3A4 | |
| SCHEMBL10355051 | 0.89 | SLC18A3 (0.54) | SLC18A3SIGMAR1GRIN2BNPC1RAB9A | |
| SCHEMBL2911926 | 0.89 | CYP11B2 (0.42) | POLBESR2SLC18A3ESR1CYP3A4 | |
| SCHEMBL5543159 | 0.89 | CYP11B2 (0.42) | POLBESR2SLC18A3ESR1CYP3A4 | |
| SCHEMBL22833 | 0.89 | CYP11B2 (0.42) | POLBESR2SLC18A3ESR1CYP3A4 | |
| SCHEMBL676555 | 0.89 | CYP11B2 (0.42) | POLBESR2SLC18A3ESR1CYP3A4 | |
| SCHEMBL1089522 | 0.87 | ESR2 (0.59) | POLBESR2SLC18A3SIGMAR1ESR1 | |
| SCHEMBL652226 | 0.87 | POLB (0.38) | POLBESR2SLC18A3SIGMAR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044227-B1 | PARTIALLY POLYMERIZED MIXTURE OF DIETHYLENE GLYCOL (ALLYL CARBONATE) COMPOUNDS | PPG IND OHIO INC (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-1044228-B1 | PROCESS FOR FORMING POLY(ALLYL CARBONATE)-FUNCTIONAL PREPOLYMER COMPOSITION | PPG IND OHIO INC (US) | 2002-07-10 | — | — | EP | disclosed |
| US-6057411-A | HEATING ALLYL CARBONATE WITH FREE RADICAL INITIATOR FOR POLYMERIZATION | PPG INDUSTRIES OHIO, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| US-5952441-A | LOW SHRINKAGE IN THE MOLD BY ADDING A PREPOLYMER COMPRISING PARTIAL POLYMERIZED ETHYLENIC DOUBLE BONDS | PPG INDUSTRIES OHIO, INC. (US) | 1999-09-14 | — | — | US | disclosed |