SCHEMBL22929

SCHEMBL22929

[c]1ccc(C2CC2)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6578876 1.00 POLB (0.46)
SCHEMBL43455 0.92 ESR2 (0.47)
SCHEMBL21538 0.92 ESR2 (0.42)
SCHEMBL10355051 0.89 SLC18A3 (0.54)
SCHEMBL2911926 0.89 CYP11B2 (0.42)
SCHEMBL5543159 0.89 CYP11B2 (0.42)
SCHEMBL22833 0.89 CYP11B2 (0.42)
SCHEMBL676555 0.89 CYP11B2 (0.42)
SCHEMBL1089522 0.87 ESR2 (0.59)
SCHEMBL652226 0.87 POLB (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1793 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 US claimed
CN-118215662-A Modulators of CCR6 receptors 爱杜西亚药品有限公司 2024-06-18 CN claimed
WO-2024118801-A1 LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS PROTEGO BIOPHARMA, INC. (US) 2024-06-06 WO claimed
CN-118055930-A Thiadiazole derivative, composition and application thereof 北京丹擎医药科技有限公司 2024-05-17 CN claimed
CN-117836296-A Pyrazolopyridone compounds 百济神州有限公司 2024-04-05 CN claimed
CN-111278816-B Dihydro quinolinones C4医药公司 2024-03-15 CN claimed
CN-111868055-B Inhibitors of TRPC6 勃林格殷格翰国际有限公司 2024-03-08 CN claimed
WO-2024022413-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE 中国石油化工股份有限公司 2024-02-01 WO claimed
WO-2024012496-A1 CANNABINOID RECEPTOR COMPOUND AND USE THEREOF 长春金赛药业有限责任公司 2024-01-18 WO claimed
WO-2024003259-A1 TEAD INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-04 WO claimed
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP claimed
WO-2004016614-A2 PYRROLOPYRAZINES AS KINASE INHIBITORS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2004-02-26 WO claimed
EP-1388541-A1 Pyrrolopyrazines as kinase inhibitors CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2004-02-11 EP claimed
EP-1261611-A2 INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE Bristol-Myers Squibb Pharma Company (US) 2002-12-04 EP claimed
US-20020065248-A1 Inhibitors of hepatitis C virus NS3 protease BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-05-30 US claimed
WO-2001064678-A2 INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-09-07 WO claimed
US-5741661-A SCREENING ASSAY CAMBRIDGE NEUROSCIENCE, INC. (US) 1998-04-21 US claimed
US-5668279-A TREATMENT OF CENTRAL NERVOUS SYSTEM DIORDERS AND GASTROINTESTINAL DISORDERS MERCK & CO., INC. (US) 1997-09-16 US claimed
US-5376503-A A photo-crosslinkable blends consisting of an isoolefin, a para-alkylstyrene and a photoinitiator substituted on the alkyl group of para-alkylstyrene monomers; corrosion, solvent resistance EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US claimed
EP-0163537-A1 1-Propanone derivatives and pharmaceutical compositions containing same TOKYO TANABE COMPANY LIMITED (JP) 1985-12-04 EP claimed