Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714676 | 0.90 | ALDH1A1 (0.61) | LMNAALDH1A1TDP1ADRB2ADRB1 | |
| SCHEMBL22833094 | 0.87 | LMNA (0.47) | LMNAALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL5433479 | 0.82 | ALDH1A1 (0.56) | LMNAALDH1A1TDP1ADRB2ADRB1 | |
| SCHEMBL1446745 | 0.82 | KMT2A (0.57) | LMNAALDH1A1TDP1ADRB2ADRB1 | |
| SCHEMBL16278307 | 0.82 | LMNA (0.52) | LMNATDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2473943 | 0.80 | LMNA (0.70) | LMNAALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL22832419 | 0.79 | LMNA (0.68) | LMNAALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL6698832 | 0.79 | LMNA (0.68) | LMNAALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL17798246 | 0.78 | ALDH1A1 (0.47) | LMNAALDH1A1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL5663225 | 0.78 | NHERF1 (0.48) | LMNAALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3990532-A1 | GLYCOL ETHER ARYL ESTER PLASTICIZER | Eastman Chemical Company (US) | 2022-05-04 | — | — | EP | disclosed |
| WO-2020263593-A1 | GLYCOL ETHER ARYL ESTER PLASTICIZER | EASTMAN CHEMICAL COMPANY (US) | 2020-12-30 | — | — | WO | disclosed |