SCHEMBL1446745

SCHEMBL1446745

CCOC(COC(=O)c1ccccc1)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
TDP1 Q9NUW8 3/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
ALDH1A1 P00352 3/20 0.51
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 3/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 3/20 0.46
GAA P10253 2/20 0.46
ADRB2 P07550 3/20 0.46
ADRB1 P08588 3/20 0.46
ADRB3 P13945 3/20 0.46
NPC1 O15118 2/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665910 0.93 KMT2A (0.66) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL714676 0.91 ALDH1A1 (0.61) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL5665304 0.86 MAPT (0.54) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL7089906 0.83 NPC1 (0.56) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL5663936 0.83 KMT2A (0.53) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL7090359 0.83 RAB9A (0.54) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL7093634 0.82 KMT2A (0.49) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL5665419 0.82 ADRB2 (0.52) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL22833247 0.82 LMNA (0.50) KMT2ATDP1SLC6A2SLC6A3ALDH1A1
SCHEMBL14461612 0.81 TDP1 (0.62) KMT2ATDP1SLC6A2SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8754019-B2 Pressure transmission medium and hydraulic device IDEMITSU KOSAN CO., LTD. (JP) 2014-06-17 US disclosed
US-20110105373-A1 PRESSURE TRANSMISSION MEDIUM AND HYDRAULIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-05-05 US disclosed
EP-2302022-A1 PRESSURE TRANSMISSION MEDIUM AND HYDRAULIC DEVICE Idemitsu Kosan Co., Ltd. (JP) 2011-03-30 EP disclosed