Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 5/20 | 0.36 |
| ▸ | SDC2 | P34741 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | VHL | P40337 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177299 | 0.89 | MAP3K5 (0.40) | SDCBPSDC2MAP3K5 | |
| SCHEMBL2177305 | 0.89 | MAP3K5 (0.40) | SDCBPSDC2MAP3K5 | |
| SCHEMBL2276572 | 0.89 | SMN1; SMN2 (0.41) | SDCBPSDC2MAPTHPGDALDH1A1 | |
| SCHEMBL2284780 | 0.88 | SDCBP (0.36) | SDCBPSDC2VHLMAPK1LMNA | |
| SCHEMBL2228136 | 0.88 | SDCBP (0.36) | SDCBPSDC2VHLMAPK1LMNA | |
| SCHEMBL13572379 | 0.88 | SDCBP (0.38) | SDCBPSDC2VHLMAPK1LMNA | |
| SCHEMBL2271028 | 0.84 | RARB (0.43) | SDCBPSDC2VHLLMNA | |
| SCHEMBL13719176 | 0.82 | TRPV1 (0.42) | MAPT | |
| SCHEMBL2181260 | 0.82 | TRPV1 (0.42) | MAPT | |
| SCHEMBL2179559 | 0.80 | TRPV1 (0.44) | SDCBPSDC2MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519500-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | Piramal Healthcare Ltd. (IN) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080718-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |