SCHEMBL228360

SCHEMBL228360

NC1=CC(=O)c2ccccc2C1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.68
NSD2 O96028 2/20 0.68
HKDC1 Q2TB90 1/20 0.68
SLC2A1 P11166 1/20 0.61
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
CDC25B P30305 4/20 0.56
MAPT P10636 4/20 0.56
MAOA P21397 4/20 0.56
ALDH1A1 P00352 3/20 0.56
IDO1 P14902 3/20 0.56
LMNA P02545 3/20 0.56
MAPK1 P28482 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
USP2 O75604 2/20 0.56
CDC25A P30304 2/20 0.56
PLIN1 O60240 2/20 0.56
BLM P54132 2/20 0.56
PLIN5 Q00G26 2/20 0.56
ABHD5 Q8WTS1 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429719 1.00 PTPN1 (0.68) PTPN1NSD2HKDC1SLC2A1MEN1
Sulfuric Acid SCHEMBL10338517 0.92 HKDC1 (0.59) PTPN1NSD2HKDC1SLC2A1MEN1
SCHEMBL28448798 0.88 PTPN1 (0.55) PTPN1NSD2HKDC1SLC2A1MEN1
4-Amino-[1,2]Naphthoquinone SCHEMBL422308 0.81 PTPN1 (1.00) PTPN1NSD2HKDC1SLC2A1MEN1
4-Amino-[1,2]Naphthoquinone SCHEMBL5051876 0.79 PTPN1 (0.95) PTPN1NSD2HKDC1SLC2A1MEN1
4-Amino-[1,2]Naphthoquinone SCHEMBL5161711 0.79 PTPN1 (0.95) PTPN1NSD2HKDC1SLC2A1MEN1
SCHEMBL31744557 0.79 GAPDH (0.49) PTPN1NSD2HKDC1SLC2A1MEN1
SCHEMBL3273421 0.77 SLC2A1 (0.96) PTPN1NSD2HKDC1SLC2A1MEN1
SCHEMBL11878878 0.77 NSD2 (0.52) PTPN1NSD2HKDC1SLC2A1MEN1
SCHEMBL7365674 0.76 MEN1 (0.65) PTPN1NSD2HKDC1SLC2A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 809 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528710-A 2, 3-Disubstituted naphthoquinone compound, application and preparation method thereof 中国农业科学院兰州畜牧与兽药研究所 2025-02-28 CN claimed
CN-116574034-B Amino naphthoquinone derivative and its preparation and use in sterilization, weeding and algae killing 青岛农业大学 2025-01-28 CN claimed
CN-118271193-A Method for promoting catalytic synthesis of 2-amino-1, 4-naphthoquinone compounds by using nicotinic acid as ligand and using dichloro-titanocene 宁夏师范学院 2024-07-02 CN claimed
US-20240141131-A1 ANTIPOLYMERANT COMPOSITIONS WITH NAPHTHOQUINONE AND HYDROXYLAMINE AND METHODS OF USING ECOLAB USA INC. 2024-05-02 US claimed
CN-116693418-A Method for C-3 cyanoalkylation of 2-amino-1, 4-naphthoquinone compounds induced by visible light 四川大学 2023-09-05 CN claimed
CN-116621844-A Organic nitrogen-containing polyquinone material, preparation method thereof and application thereof in organic lithium ion battery 常州大学 2023-08-22 CN claimed
CN-116574034-A Amino naphthoquinone derivative and its preparation and use in sterilization, weeding and algae killing 青岛农业大学 2023-08-11 CN claimed
CN-115286594-B With S 8 Method for synthesizing quinone thiazole compounds as raw materials 浙江工业大学 2023-07-25 CN claimed
CN-115483387-A Positive electrode active material, preparation method thereof, composite positive electrode and water-based zinc ion battery 石河子大学 2022-12-16 CN claimed
CN-115286594-A With S 8 Method for synthesizing quinothiazole compounds as raw materials 浙江工业大学 2022-11-04 CN claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
US-5116958-A Containing releasable oxime or lactam group CIBA-GEIGY CORPORATION (US) 1992-05-26 US claimed
US-5059662-A Method for producing ethylene copolymer RESENE PRODUCTS COMPANY (US) 1991-10-22 US claimed
EP-0240047-B1 FUNGICIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-01-02 EP claimed
EP-0240047-A1 Fungicides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-10-07 EP claimed
CN-87101634-A Mycocide 1987-09-30 CN claimed
US-4628062-A 1,4-naphthoquinone derivatives having anti-inflammatory action TROPONWERKE GMBH & CO., KG (DE) 1986-12-09 US claimed
US-4220528-A CONTACTING A GAS WITH A SOLUTION CONTAINING A HYDRAZINE, A QUINONE, AN ALKALI; CONTACTING THE DEOXYGENATED GAS WITH WATER OTSUKA CHEMICAL CO., LTD. (JP) 1980-09-02 US claimed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US claimed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US claimed