SCHEMBL28448798

SCHEMBL28448798

NC1=CC(=O)c2ccccc2C1=O.c1ccc2c(c1)[Se]2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.55
NSD2 O96028 2/20 0.55
HKDC1 Q2TB90 1/20 0.55
SLC2A1 P11166 1/20 0.50
S100A4 P26447 3/20 0.46
TGM2 P21980 1/20 0.46
PADI1 Q9ULC6 1/20 0.46
PADI3 Q9ULW8 1/20 0.46
PADI4 Q9UM07 1/20 0.46
PADI2 Q9Y2J8 1/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 3/20 0.46
CDC25B P30305 3/20 0.46
KMT2A Q03164 3/20 0.46
USP2 O75604 2/20 0.46
IDO1 P14902 2/20 0.46
CDC25A P30304 2/20 0.46
LMNA P02545 2/20 0.46
MAPK1 P28482 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429719 0.88 PTPN1 (0.68) PTPN1NSD2HKDC1SLC2A1S100A4
SCHEMBL228360 0.88 PTPN1 (0.68) PTPN1NSD2HKDC1SLC2A1S100A4
Sulfuric Acid SCHEMBL10338517 0.81 HKDC1 (0.59) PTPN1NSD2HKDC1SLC2A1S100A4
4-Amino-[1,2]Naphthoquinone SCHEMBL422308 0.71 PTPN1 (1.00) PTPN1NSD2HKDC1SLC2A1S100A4
4-Amino-[1,2]Naphthoquinone SCHEMBL5051876 0.70 PTPN1 (0.95) PTPN1NSD2HKDC1SLC2A1S100A4
4-Amino-[1,2]Naphthoquinone SCHEMBL5161711 0.70 PTPN1 (0.95) PTPN1NSD2HKDC1SLC2A1S100A4
SCHEMBL31744557 0.69 GAPDH (0.49) PTPN1NSD2HKDC1SLC2A1S100A4
SCHEMBL3273421 0.68 SLC2A1 (0.96) PTPN1NSD2HKDC1SLC2A1S100A4
SCHEMBL11878878 0.68 NSD2 (0.52) PTPN1NSD2HKDC1SLC2A1S100A4
SCHEMBL7365674 0.67 MEN1 (0.65) PTPN1NSD2HKDC1SLC2A1S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111606843-A Synthetic method of 2-phenylseleno-3-amino-1, 4-naphthoquinone 温州医科大学 2020-09-01 CN disclosed