SCHEMBL22837460

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22837524	0.92	ALOX5 (0.40)	MCL1ACMSDALOX5CA12CA1
	SCHEMBL17703120	0.91	MCL1 (0.40)	MCL1ACMSDALOX5CA12CA1
	SCHEMBL29362475	0.91	MCL1 (0.40)	MCL1ACMSDALOX5CA12CA1
	SCHEMBL17703149	0.90	ENPP3 (0.38)	MCL1ACMSDALOX5CA12CA1
	SCHEMBL27334347	0.90	CYP1A1 (0.39)	MCL1ACMSDCA12CA1CA2
	SCHEMBL26753130	0.89	ALDH1A1 (0.36)	MCL1ACMSDALOX5CA12CA1
	SCHEMBL24944602	0.89	PRKDC (0.36)	ALOX5CA12CA1CA2CA9
	SCHEMBL19103123	0.89	MCL1 (0.38)	MCL1ACMSDALOX5CA12CA1
	SCHEMBL24945261	0.89	PRKDC (0.36)	ALOX5CA12CA1CA2CA9
	SCHEMBL26588805	0.89	ALOX5 (0.43)	MCL1ACMSDALOX5CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.