Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.58 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832991 | 0.96 | ALDH1A1 (0.65) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL4885809 | 0.94 | MAPT (0.68) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL15872025 | 0.89 | ALDH1A1 (0.55) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL26418659 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL7931333 | 0.84 | HTR3A (0.61) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL2092264 | 0.84 | MAPT (0.50) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL14504494 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL7923952 | 0.83 | HTR1A (0.58) | ALDH1A1MAPTMCOLN3MEN1KMT2A | |
| SCHEMBL28188649 | 0.83 | SLC18A3 (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL3420619 | 0.83 | MAPT (0.56) | ALDH1A1MAPTMCOLN3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648245-A | Tetrahydroquinoline derivative and medical application thereof | 东丽株式会社 | 2023-08-25 | — | — | CN | disclosed |
| EP-3455226-B1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-12-30 | — | — | EP | disclosed |