Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20863035 | 0.88 | KCNH2 (0.42) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL11743635 | 0.86 | KCNA5 (0.42) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL27588961 | 0.84 | KCNA5 (0.44) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL8972603 | 0.84 | KCNA5 (0.44) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL27269583 | 0.84 | — | — | |
| SCHEMBL3176857 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL5980403 | 0.80 | USP2 (0.41) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL516841 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL3248168 | 0.79 | SLC6A3 (0.41) | — | |
| SCHEMBL9738640 | 0.77 | KMT2A (0.39) | ALDH1A1LMNAKMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030327-B2 | 3-[1-(2-chlorophenyl)ethoxy]-5-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxyamide; polo like kinase inhibitor; antitumor and anticarcinogenic agent; mitotic phase (M phase) of the cell cycle | MDS K.K. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-7998949-B2 | Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-16 | — | — | US | disclosed |
| EP-1702960-B1 | Pigment dispersing agent, pigment composition and pigment dispersion | TOYO INK MFG CO (JP) | 2010-05-12 | — | — | EP | disclosed |
| US-20080103136-A1 | Novel Fused Imidazole Derivative | MSD K.K. (JP) | 2008-05-01 | — | — | US | disclosed |
| US-7147704-B2 | Pigment dispersing agent, pigment composition and pigment dispersion | TOKYO INK MFG. CO., LTD (JP) | 2006-12-12 | — | — | US | disclosed |
| US-20060207478-A1 | Dispersant has a quinophthalone structure bonded to a triazine structure through an arylene or a heteroaromatic ring and having a basic functional group bonded to the triazine ring through a connecting group; improved fluidity; improved tinting strength, transparency and viscosity stability | TOYO INK MFG. CO., LTD. (JP) | 2006-09-21 | — | — | US | disclosed |
| EP-1702960-A2 | Pigment dispersing agent, pigment composition and pigment dispersion | TOYO INK MFG. CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| EP-1022273-B1 | Pigment composition containing a pigment dispersing agent | TOYO INK MFG CO (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-0955275-B1 | Coating composition for coloring a glass, process for the preparation thereof and use thereof | TOYO INK MFG CO (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6333371-B1 | Coating composition for coloring a glass, process for the production thereof and use thereof | TOYO INK MFG. CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1052230-A1 | Coating composition for coloring glass | TOYO INK MANUFACTURING CO., LTD. (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-6123763-A | PROVIDES AN INK OR A COATING COMPOSITIONFREEDOM OF AGGREGATION, NON-CRYSTALLIZABILITY AND FLUIDITY, | TOYO INK MFG. CO., LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0710706-B1 | Method for dispersing pigment and water-based pigment dispersion | TOYO INK MFG CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-1022273-A1 | Pigment dispersing agent and pigment composition containing the same | TOYO INK MANUFACTURING CO., LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |
| EP-0955275-A1 | Coating composition for coloring a glass, process for the preparation thereof and use thereof | TOYO INK MANUFACTURING CO., LTD. (JP) | 1999-11-10 | — | — | EP | disclosed |
| US-5635552-A | MIXTURES OF PIGMENT, DISPERSANT, WATER-BASED RESIN AND WATER SOLUBLE SOLVENT, FOR COATINGS, INKS | TOYO INK MANUFACTURING CO., LTD. (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0710706-A2 | Method for dispersing pigment and water-based pigment dispersion | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5476544-A | Dispersing agent | TOYO INK MANUFACTURING CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-4664714-A | TRIAZINE-CONTAINING DISPERSANT | TOYO INK MANUFACTURING CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4005085-A | SEDATIVES, ANTI-CONVULSANTS, MUSCLE RELAXANTS AND ANXIOLYTIC ACTIVITIES | HOFFMANN-LA ROCHE INC. (US) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103136-A1 | Novel Fused Imidazole Derivative | HRH4, H1-4, H1-3 | ALDH1A1 1939/4885LMNA 3610/4885KMT2A 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.