Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | DBH | P09172 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272693 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| Ethylene SCHEMBL28028832 | 0.81 | KDM4E (0.51) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11532141 | 0.75 | POLB (0.50) | DBHPOLB | |
| Benzaldehyde SCHEMBL5801520 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL5792155 | 0.74 | MMP2 (0.34) | ALDH1A1DBHKMT2AMEN1MAPT | |
| SCHEMBL11580947 | 0.74 | ALDH1A1 (0.36) | ALDH1A1DBHKMT2AMEN1MAPT | |
| SCHEMBL8656963 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL9420347 | 0.72 | KMT2A (0.52) | ALDH1A1KMT2AMEN1APOBEC3GKDM4E | |
| SCHEMBL41241 | 0.71 | KDM1A (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2APOBEC3G | |
| SCHEMBL27672161 | 0.71 | KDM1A (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9802937-B2 | Substituted pyrazolo{4,3-D}pyrimidines as kinase inhibitors | ORIGENIS GMBH (DE) | 2017-10-31 | — | — | US | disclosed |
| US-9642809-B2 | Controlled release pharmaceutical compositions for prolonged effect | EGALET LTD. (GB) | 2017-05-09 | — | — | US | disclosed |
| US-9587016-B2 | Treatment method for lung remodeling diseases | FIBROGEN, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| CN-106255414-A | S benzylthiouracil compound and the method strengthening plant root growth | 瓦伦特生物科学公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-106255414-A | S benzylthiouracil compound and the method strengthening plant root growth | 瓦伦特生物科学公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-106255414-A | S benzylthiouracil compound and the method strengthening plant root growth | 瓦伦特生物科学公司 | 2016-12-21 | — | — | CN | disclosed |
| US-9510593-B2 | S-benzylthiouracil compounds and methods of enhancing plant root growth | VALENT BIOSCIENCES CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| EP-3094181-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | Valent Biosciences Corporation (US) | 2016-11-23 | — | — | EP | disclosed |
| US-9499535-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| EP-2699572-B1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2016-08-10 | — | — | EP | disclosed |
| WO-2008091167-A1 | TOPICAL FORMULATION | BOMAC RESEARCH LIMITED (NZ) | 2008-07-31 | — | — | WO | disclosed |
| US-7335379-B2 | Transdermal pharmaceutical formulation for minimizing skin residues | ANTARES PHARMA IPL AG (CH) | 2008-02-26 | — | — | US | disclosed |
| US-20060153905-A1 | Transdermal pharmaceutical formulation for minimizing skin residues | ANTARES PHARMA, INC. | 2006-07-13 | — | — | US | disclosed |
| EP-1670433-A1 | TRANSDERMAL PHARMACEUTICAL FORMULATION FOR MINIMIZING SKIN RESIDUES | Antares Pharma IPL AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005039531-A1 | TRANSDERMAL PHARMACEUTICAL FORMULATION FOR MINIMIZING SKIN RESIDUES | ANTARES PHARMA IPL AG (CH) | 2005-05-06 | — | — | WO | disclosed |
| EP-1169310-A1 | PROCESS FOR PREPARING MKC-442 | Triangle Pharmaceuticals Inc. (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000061566-A1 | PROCESS FOR PREPARING MKC-442 | TRIANGLE PHARMACEUTICALS, INC. (US) | 2000-10-19 | — | — | WO | disclosed |
| EP-0093653-B1 | PROCESS FOR THE PREPARATION OF IODO-THYRONINES AND IODO-THYROACETIC ACIDS BY ELECTROCHEMICAL REDUCTION AT A CONTROLLED POTENTIAL | SPIRAL Société à responsabilité limitée dite : (FR) | 1985-07-10 | — | — | EP | disclosed |
| US-4490221-A | Process for preparing iodothyronines and iodothyroacetic acids by electrochemical reduction at controlled potential | SPIRAL SOCIETE A RESPONSABILITE LIMITEE DITE (FR) | 1984-12-25 | — | — | US | disclosed |
| EP-0093653-A1 | Process for the preparation of iodo-thyronines and iodo-thyroacetic acids by electrochemical reduction at a controlled potential | SPIRAL Société à responsabilité limitée dite : (FR) | 1983-11-09 | — | — | EP | disclosed |