Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272693 | 0.96 | ALDH1A1 (0.53) | KDM4EPKML3MBTL1ALDH1A1HPGD | |
| Benzaldehyde SCHEMBL5801520 | 0.85 | ALDH1A1 (0.44) | KDM4EPKML3MBTL1ALDH1A1HPGD | |
| SCHEMBL2284398 | 0.81 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDCYP3A4GSK3A | |
| SCHEMBL9173089 | 0.79 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1HPGDCYP3A4KMT2A | |
| SCHEMBL20791876 | 0.79 | P2RX4 (0.50) | KDM4EALDH1A1P2RX4SMN1; SMN2MEN1 | |
| SCHEMBL23498217 | 0.78 | ALDH1A1 (0.54) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9394061 | 0.77 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1HPGDCYP3A4F2 | |
| SCHEMBL319867 | 0.76 | ALDH1A1 (0.53) | KDM4EL3MBTL1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL7255032 | 0.76 | C5AR1 (0.47) | KDM4EALDH1A1HPGDCYP3A4P2RX4 | |
| SCHEMBL23517947 | 0.76 | HDAC1 (0.50) | ALDH1A1HPGDMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968418-A | signal responsive solute | MCGINNIS ROBERT | 2015-10-07 | — | — | CN | claimed |
| CN-104968418-A | signal responsive solute | MCGINNIS ROBERT | 2015-10-07 | — | — | CN | disclosed |