Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23735659 | 0.84 | FAAH (0.53) | GAARECQLDEGS1FAAHALDH1A1 | |
| SCHEMBL21029837 | 0.83 | RECQL (0.44) | GAARECQLDEGS1FAAHALDH1A1 | |
| SCHEMBL22692705 | 0.82 | TSHR (0.46) | GAAFAAHALDH1A1KMT2AMEN1 | |
| SCHEMBL27251492 | 0.82 | FAAH (0.55) | GAARECQLDEGS1FAAHALDH1A1 | |
| SCHEMBL8165113 | 0.81 | LMNA (0.41) | DEGS1ALDH1A1KMT2ALMNA | |
| SCHEMBL21029695 | 0.81 | ALDH1A1 (0.50) | GAARECQLDEGS1FAAHALDH1A1 | |
| SCHEMBL23735666 | 0.81 | POLB (0.49) | GAARECQLDEGS1FAAHALDH1A1 | |
| SCHEMBL23729882 | 0.81 | FAAH (0.42) | GAADEGS1FAAHALDH1A1CYP3A4 | |
| SCHEMBL17235958 | 0.81 | RECQL (0.56) | GAARECQLFAAHALDH1A1KMT2A | |
| SCHEMBL25109864 | 0.79 | GLP1R (0.42) | DEGS1FAAHALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |
| US-20200407724-A1 | TARGETED COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-12-31 | — | — | US | disclosed |
| US-20160326299-A1 | NOVEL NOVOLAC CURING AGENT WITH ALKOXYSILYL GROUP, METHOD FOR PREPARING THE SAME, COMPOSITION CONTAINING THE SAME, THE CURED PRODUCT, AND USE THEREOF | KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) | 2016-11-10 | — | — | US | disclosed |