Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23317392 | 0.88 | NR1I2 (0.41) | DAOCA2ALDH1A1HPGD | |
| SCHEMBL23079345 | 0.84 | CA2 (0.38) | DAOCA2ALDH1A1HPGD | |
| SCHEMBL24272221 | 0.79 | CA2 (0.31) | DAOCA2 | |
| SCHEMBL10141583 | 0.74 | DAO (0.44) | DAOTP53RAB9AALDH1A1HPGD | |
| SCHEMBL22432014 | 0.69 | CA2 (0.39) | CA2 | |
| SCHEMBL29256493 | 0.68 | DAO (0.43) | DAOTP53RAB9ACA2ALDH1A1 | |
| SCHEMBL17428955 | 0.66 | LMNA (0.45) | DAOTP53RAB9AALDH1A1HPGD | |
| SCHEMBL1700982 | 0.66 | DAO (0.41) | DAOTP53RAB9AALDH1A1LMNA | |
| SCHEMBL13848615 | 0.65 | CHRNB2 (0.36) | — | |
| SCHEMBL23057961 | 0.65 | CA2 (0.38) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264176-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RTI INTERNATIONAL (US) | 2020-12-30 | — | — | WO | disclosed |