Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22845611 | 0.85 | ALDH1A1 (0.46) | FLT3MIFKDRPIK3CAPRMT5 | |
| SCHEMBL23051045 | 0.85 | FLT3 (0.56) | FLT3MIFKDRPIK3CAPRMT5 | |
| SCHEMBL22845607 | 0.75 | PKM (0.42) | FLT3MIFKDRPIK3CAIKBKE | |
| SCHEMBL22845640 | 0.74 | CDK8 (0.49) | KDR | |
| SCHEMBL22845613 | 0.74 | PLK1 (0.39) | FLT3MIFKDRPIK3CAIKBKE | |
| SCHEMBL2650330 | 0.73 | FLT3 (0.74) | FLT3MIFKDRPIK3CAKIT | |
| SCHEMBL22851709 | 0.71 | FLT3 (0.71) | FLT3MIFKDRPIK3CAPRMT5 | |
| SCHEMBL23051047 | 0.70 | FLT3 (0.71) | FLT3MIFKDRPIK3CAFYN | |
| SCHEMBL14668453 | 0.69 | FLT3 (0.60) | FLT3MIFKDRPIK3CAPRMT5 | |
| SCHEMBL22044029 | 0.68 | IKBKE (0.55) | FLT3MIFIKBKETBK1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263187-A1 | COMPOUNDS FOR TREATMENT OF EYE DISORDERS | SINOPSEE THERAPEUTICS (SG) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020263186-A1 | COMPOUNDS FOR TREATMENT OF CANCER | SINOPSEE THERAPEUTICS (SG) | 2020-12-30 | — | — | WO | disclosed |