Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.61 |
| ▸ | RARG | P13631 | 9/20 | 0.61 |
| ▸ | RARA | P10276 | 7/20 | 0.61 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | BLVRB | P30043 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 14/20 | 0.54 |
| ▸ | RXRB | P28702 | 12/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049073 | 0.88 | CYP3A4 (0.54) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL5180319 | 0.86 | RARB (0.59) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7723495 | 0.84 | RARB (0.74) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8557337 | 0.82 | RARB (0.73) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9117662 | 0.82 | RARB (0.68) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL22845645 | 0.81 | RXRA (0.60) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL5680243 | 0.79 | RARB (0.71) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL11564878 | 0.77 | HCAR3 (0.83) | HCAR3 | |
| SCHEMBL11563648 | 0.77 | HCAR3 (0.63) | MEN1KMT2AHCAR3 | |
| SCHEMBL8552419 | 0.77 | RARA (0.71) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263960-A1 | COMPOSITIONS COMPRISING A RETINOID X RECEPTOR (RXR) AGONIST, A RETINOIC ACID RECEPTOR (RAR) AGONIST, OR A DUAL RXR/RAR AGONIST | WAGNER CARL (US) | 2020-12-30 | — | — | WO | disclosed |