Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529006 | 0.84 | L3MBTL3 (0.81) | L3MBTL3L3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL22175018 | 0.83 | KMT2A (0.62) | L3MBTL3L3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL22570271 | 0.83 | ALDH1A1 (0.53) | L3MBTL3L3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL14528437 | 0.83 | L3MBTL3 (0.73) | L3MBTL3L3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL8587266 | 0.83 | L3MBTL3 (0.43) | L3MBTL3L3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL22848099 | 0.82 | KMT2A (0.65) | L3MBTL3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL2777044 | 0.82 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1MAPTTP53 | |
| SCHEMBL2780493 | 0.82 | KMT2A (0.65) | L3MBTL3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL15764103 | 0.82 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1MAPTTP53 | |
| SCHEMBL2780491 | 0.82 | KMT2A (0.65) | L3MBTL3L3MBTL1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11517568-B2 | Compounds and methods for treating nematode infections | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-12-06 | — | — | US | disclosed |
| US-20200405710-A1 | COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405710-A1 | COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS | HNMT, HRH2, NISCH | L3MBTL3 2185/4885L3MBTL1 1758/4885ALDH1A1 619/4885 |
| US-11517568-B2 | Compounds and methods for treating nematode infections | HNMT, HRH2, NISCH | L3MBTL3 2185/4885L3MBTL1 1758/4885ALDH1A1 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.