Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265731 | 0.92 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1MAPTNPC1ALDH1A1 | |
| SCHEMBL22848339 | 0.83 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1TP53MAPTNPC1 | |
| SCHEMBL3795448 | 0.75 | LGMN (0.54) | TP53MAPTNPC1ALDH1A1 | |
| SCHEMBL14761576 | 0.72 | LMNA (0.48) | TP53ALDH1A1ABCB1 | |
| SCHEMBL6134210 | 0.71 | MEN1 (0.46) | L3MBTL3L3MBTL1MAPTHRH3 | |
| SCHEMBL16374578 | 0.70 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1ALDH1A1HRH3 | |
| SCHEMBL19958761 | 0.70 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1ALDH1A1HRH3 | |
| SCHEMBL7473734 | 0.70 | POLB (0.48) | TP53MAPTALDH1A1SIGMAR1 | |
| SCHEMBL14529006 | 0.69 | L3MBTL3 (0.81) | L3MBTL3L3MBTL1TP53MAPTNPC1 | |
| SCHEMBL6134434 | 0.69 | ALDH1A1 (0.49) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925291-A1 | SPIROCYCLIC DOPAMINE RECEPTOR SUBTYPE LIGANDS | PFIZER INC. (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998008835-A1 | SPIROCYCLIC DOPAMINE RECEPTOR SUBTYPE LIGANDS | PFIZER INC. (US) | 1998-03-05 | — | — | WO | disclosed |