SCHEMBL22848429

SCHEMBL22848429

O=C1C(=C/C=C2/N(Cc3cccc4ccccc34)c3ccc4ccccc4c3C23CCCCC3)C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
OPRL1 P41146 1/20 0.33
SCN9A Q15858 1/20 0.32
MDM2 Q00987 2/20 0.31
P2RX4 Q99571 1/20 0.31
PSEN1 P49768 2/20 0.31
PSEN2 P49810 2/20 0.31
APH1B Q8WW43 2/20 0.31
NCSTN Q92542 2/20 0.31
APH1A Q96BI3 2/20 0.31
PSENEN Q9NZ42 2/20 0.31
NPBWR1 P48145 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PRMT1 Q99873 2/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848485 0.91 HTT (0.32)
SCHEMBL22848467 0.79 MAPT (0.32)
SCHEMBL22848430 0.78 NR1H2 (0.35)
SCHEMBL22848456 0.78 TP53 (0.31)
SCHEMBL22848455 0.78 METAP2 (0.31)
SCHEMBL22848428 0.76 CYP1B1 (0.33) CA2
SCHEMBL22848427 0.75 MAPK14 (0.32)
SCHEMBL22848188 0.75 TP53 (0.31)
SCHEMBL22848246 0.67 HSP90AA1 (0.34)
SCHEMBL22848447 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed