SCHEMBL22848485

SCHEMBL22848485

O=C1C(=C/C=C2\N(Cc3ccnc4ccccc34)c3ccc4ccccc4c3C23CCCCC3)C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.32
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848429 0.91 DRD2 (0.34)
SCHEMBL22848427 0.75 MAPK14 (0.32) HTTKDM4EALDH1A1SMN1; SMN2
SCHEMBL22848428 0.75 CYP1B1 (0.33) ALDH1A1
SCHEMBL22848467 0.74 MAPT (0.32) KDM4EALDH1A1LMNA
SCHEMBL22848430 0.74 NR1H2 (0.35)
SCHEMBL22848455 0.73 METAP2 (0.31) HTTALDH1A1
SCHEMBL22848456 0.73 TP53 (0.31)
SCHEMBL22848494 0.70 NMT1 (0.30)
SCHEMBL22848188 0.70 TP53 (0.31)
SCHEMBL22848459 0.69 SMN1; SMN2 (0.30) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed