SCHEMBL22851963

SCHEMBL22851963

Cc1ccc2c3ccc4c5cccc(C)c5n(-c5ccccc5)c4c3n(-c3cccc(-n4c5ccccc5c5ccccc54)c3)c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.46
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALKBH5 Q6P6C2 1/20 0.43
FTO Q9C0B1 1/20 0.43
CYP1A2 P05177 2/20 0.36
TP53 P04637 3/20 0.34
ALDH1A1 P00352 3/20 0.34
LMNA P02545 3/20 0.34
PLA2G10 O15496 2/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 4/20 0.33
RXFP1 Q9HBX9 1/20 0.33
REN P00797 2/20 0.32
MAT2A P31153 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GLA P06280 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17166721 0.91 ALKBH5 (0.47) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL26451730 0.88 KDM4E (0.53) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL883779 0.88 KDM4E (0.55) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL12456485 0.87 KDM4E (0.49) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL23615513 0.85 KDM4E (0.39) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL8739856 0.85 KDM4E (0.53) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL16976993 0.83 L3MBTL1 (0.53) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL12939252 0.83 KDM4E (0.61) ATMKDM4EL3MBTL1ALKBH5FTO
SCHEMBL883474 0.83 KDM4E (0.67) ATMKDM4EL3MBTL1ALDH1A1LMNA
SCHEMBL31216324 0.83 KDM4E (0.61) ATMKDM4EL3MBTL1ALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3770985-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2021-01-27 EP disclosed
US-20200411772-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-12-31 US disclosed