Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26451730 | 0.94 | KDM4E (0.53) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL883782 | 0.92 | KDM4E (0.53) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL883474 | 0.91 | KDM4E (0.67) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL15451799 | 0.90 | KDM4E (0.59) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL16976993 | 0.89 | L3MBTL1 (0.53) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL10206196 | 0.88 | KDM4E (0.50) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL10206157 | 0.88 | KDM4E (0.50) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL1104947 | 0.88 | KDM4E (0.62) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL17589474 | 0.88 | KDM4E (0.42) | KDM4EATML3MBTL1HTTMAPT | |
| SCHEMBL22851963 | 0.88 | ATM (0.46) | KDM4EATML3MBTL1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2019-09-12 | — | — | US | disclosed |
| US-10374170-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2651862-B1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| EP-3121183-A1 | METALS CONTAINING ORGANIC COMPLEXES | Merck Patent GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
| EP-2896627-B1 | Metals containing organic complexes | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-20150057445-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| EP-2593184-B1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND THE USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012079678-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012038029-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012007103-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | KDM4E 710/4885ATM 1550/4885L3MBTL1 1480/4885 |
| US-10374170-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | KDM4E 710/4885ATM 1550/4885L3MBTL1 1480/4885 |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | KDM4E 710/4885ATM 1550/4885L3MBTL1 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.