SCHEMBL8739856

SCHEMBL8739856

Cc1ccc2c3ccccc3n(-c3cccc(-n4c5ccccc5c5ccc(C)cc54)c3)c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 3/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.41
KIF11 P52732 1/20 0.38
GPR3 P46089 1/20 0.38
TP53 P04637 1/20 0.38
MAT2A P31153 1/20 0.37
ALKBH5 Q6P6C2 1/20 0.37
FTO Q9C0B1 1/20 0.37
PMM2 O15305 1/20 0.36
MPI P34949 1/20 0.36
PHOSPHO1 Q8TCT1 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
FGFR1 P11362 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26226128 0.94 KDM4E (0.47) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL8739857 0.93 CYP1A2 (0.41) KDM4EATML3MBTL1MAPTMAT2A
SCHEMBL8739861 0.92 KDM4E (0.48) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL10090560 0.92 KDM4E (0.48) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL883474 0.91 KDM4E (0.67) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL16593078 0.90 KDM4E (0.60) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL8739874 0.89 KDM4E (0.53) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL8739863 0.89 KDM4E (0.53) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL8739855 0.89 KDM4E (0.53) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL4401736 0.89 KDM4E (0.57) KDM4EATML3MBTL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-9193747-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-11-24 US disclosed
US-8735878-B2 Charge transporting material and organic electroluminescence device UDC IRELAND LIMITED (IE) 2014-05-27 US disclosed
US-8679649-B2 Material for organic electroluminescence device, and organic electroluminescence device UDC IRELAND LIMITED (IE) 2014-03-25 US disclosed
US-20130270530-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND UDC IRELAND LIMITED (IE) 2013-10-17 US disclosed
US-20120256173-A1 CHARGE TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-10-11 US disclosed
US-20120169218-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-07-05 US disclosed
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 KDM4E 2299/4885ATM 3234/4885L3MBTL1 963/4885
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE SLC26A3, SLC43A3, SLCO2A1 KDM4E 4092/4885ATM 3592/4885L3MBTL1 1106/4885
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device VCL, L1CAM, EML4 KDM4E 374/4885ATM 1530/4885L3MBTL1 342/4885
US-20120256173-A1 CHARGE TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE SLCO4C1, SLC39A3, SLC39A11 KDM4E 3988/4885ATM 4617/4885L3MBTL1 570/4885
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE VCL, L1CAM, EML4 KDM4E 374/4885ATM 1530/4885L3MBTL1 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.