Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294527 | 1.00 | KCNMA1 (0.56) | KCNMA1MEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL30294446 | 0.90 | LMNA (0.52) | KCNMA1MEN1KMT2AMAPTHTT | |
| SCHEMBL30294462 | 0.89 | KCNMA1 (0.56) | KCNMA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL22853477 | 0.89 | KCNMA1 (0.56) | KCNMA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL30294465 | 0.89 | KCNMA1 (0.56) | KCNMA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL22853031 | 0.85 | KMT2A (0.51) | KCNMA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL30294853 | 0.85 | KMT2A (0.51) | KCNMA1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1095516 | 0.82 | MEN1 (0.64) | KCNMA1MEN1KMT2AMAPTHTT | |
| SCHEMBL29812845 | 0.82 | MEN1 (0.64) | KCNMA1MEN1KMT2AMAPTHTT | |
| SCHEMBL19075923 | 0.81 | CYP46A1 (0.53) | KMT2AMAPTHSP90AA1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |