Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874452 | 0.96 | ALDH1A1 (0.47) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30839543 | 0.85 | ALDH1A1 (0.44) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL4735612 | 0.84 | ALDH1A1 (0.54) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL731621 | 0.82 | HMGB1 (0.55) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| Hydrochloric Acid SCHEMBL4422370 | 0.81 | HMGB1 (0.53) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3828592 | 0.80 | KDM4E (0.50) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30177551 | 0.80 | ALDH1A1 (0.50) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3262902 | 0.79 | ALDH1A1 (0.45) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL363595 | 0.79 | BCAT2 (0.48) | BCAT2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL31721455 | 0.79 | FOLH1 (0.66) | ALDH1A1KDM4EMAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212049-B2 | Electronically tuned ligands for asymmetric hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-03 | — | — | US | disclosed |
| US-20110257393-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-20 | — | — | US | disclosed |
| US-7994335-B2 | Electronically tuned ligands for asymmetric hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20100041898-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-18 | — | — | US | disclosed |
| WO-2008067218-A1 | ELECTRONICALLY TUNED LIGANDS FOR ASYMMETRIC HYDROGENATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-05 | — | — | WO | disclosed |
| EP-1218388-B1 | ELECTRONICALLY TUNED LIGANDS | BOEHRINGER INGELHEIM PHARMA (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1218388-A1 | ELECTRONICALLY TUNED LIGANDS | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| US-6316620-B1 | AS LIGANDS TO TRANSITION METALS WHICH ARE USED AS CATALYSTS IN SYNTHESIZING ASYMMETRIC COMPOUNDS TO OBTAIN SPECIFIC ENANTIOMERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | disclosed |
| WO-2001018012-A1 | ELECTRONICALLY TUNED LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041898-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BID, HDHD5, HRH4 | BCAT2 2576/4885ALDH1A1 2836/4885KDM4E 4189/4885 |
| US-20110257393-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BID, HDHD5, HRH4 | BCAT2 2576/4885ALDH1A1 2836/4885KDM4E 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.