Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20696479 | 0.89 | TSHR (0.53) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL20060321 | 0.83 | ALDH1A1 (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL25007355 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL17067685 | 0.80 | TSHR (0.58) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL22418021 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL23334173 | 0.79 | THRB (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL22198349 | 0.76 | TSHR (0.53) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27122429 | 0.75 | ALDH1A1 (0.51) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL15682924 | 0.75 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| 2-Methoxyethanol SCHEMBL23928708 | 0.75 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264327-A1 | EXTRACELLULAR MATRICES, USES THEREOF, AND METHODS OF MAKING EXTRACELLULAR MATRICES | GEMSTONE BIOTHERAPEUTICS LLC (US) | 2020-12-30 | — | — | WO | disclosed |