Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenicarbazide SCHEMBL250264 | 1.00 | ALOX5 (0.61) | ALOX5TSHRCYP3A4PTGS2GAA | |
| Phenicarbazide SCHEMBL27711804 | 0.98 | ALOX5 (0.59) | ALOX5TSHRCYP3A4PTGS2GAA | |
| SCHEMBL5075214 | 0.87 | PEPD (0.52) | ALOX5TSHRCYP3A4PTGS2GAA | |
| SCHEMBL10594245 | 0.87 | PTPN1 (0.50) | ALOX5TSHRCYP3A4PTGS2GAA | |
| SCHEMBL9800314 | 0.86 | ALOX5 (0.52) | ALOX5TSHRCYP3A4PTGS2GAA | |
| Phenicarbazide SCHEMBL8993011 | 0.84 | ALOX5 (0.46) | ALOX5TSHRCYP3A4PTGS2GAA | |
| Hydrazobenzene SCHEMBL10946311 | 0.82 | ALDH1A1 (0.67) | ALOX5TSHRCYP3A4PTGS2GAA | |
| SCHEMBL1520818 | 0.82 | ALDH1A1 (0.60) | ALOX5TSHRCYP3A4PTGS2GAA | |
| SCHEMBL9179118 | 0.81 | PEPD (0.64) | ALOX5TSHRCYP3A4PTGS2GAA | |
| SCHEMBL13434772 | 0.80 | ALDH1A1 (0.69) | ALOX5TSHRCYP3A4PTGS2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264490-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |