Phenicarbazide

Phenicarbazide

SCHEMBL8993011

NC(=O)NNc1ccccc1.NN(CC(=O)O)CC(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
PTGS2 P35354 2/20 0.44
GAA P10253 8/20 0.42
SMN1; SMN2 Q16637 4/20 0.41
ALDH1A1 P00352 2/20 0.41
CA1 P00915 6/20 0.41
CA2 P00918 6/20 0.41
KDM4E B2RXH2 1/20 0.41
F2 P00734 1/20 0.40
ALOX12 P18054 1/20 0.40
CYP2C19 P33261 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
GFER P55789 1/20 0.40
CA4 P22748 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22856571 0.84 ALOX5 (0.61) ALOX5CYP3A4TSHRPTGS2GAA
Phenicarbazide SCHEMBL250264 0.84 ALOX5 (0.61) ALOX5CYP3A4TSHRPTGS2GAA
Phenicarbazide SCHEMBL27711804 0.82 ALOX5 (0.59) ALOX5CYP3A4TSHRPTGS2GAA
SCHEMBL5075214 0.73 PEPD (0.52) ALOX5CYP3A4TSHRPTGS2GAA
SCHEMBL10594245 0.73 PTPN1 (0.50) ALOX5CYP3A4TSHRPTGS2GAA
SCHEMBL9800314 0.72 ALOX5 (0.52) ALOX5CYP3A4TSHRPTGS2GAA
Glycine SCHEMBL28995067 0.69 GAA (0.49) ALOX5CYP3A4TSHRPTGS2GAA
Hydrazobenzene SCHEMBL10946311 0.69 ALDH1A1 (0.67) ALOX5CYP3A4TSHRPTGS2GAA
SCHEMBL8601895 0.69 GAA (0.58) TSHRGAASMN1; SMN2ALDH1A1CA1
SCHEMBL21055737 0.69 ALOX5 (0.63) ALOX5CYP3A4TSHRPTGS2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541044-A USING A MALONDIAMIDE-TYPE YELLOW COUPLER AND A DEVELOPMENT INHIBITOR RELEASE (DIR) COMPOUND; SHARPNESS; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1996-07-30 US disclosed
EP-0513496-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-11-19 EP disclosed