Phenicarbazide

Phenicarbazide

SCHEMBL250264

NC(=O)NNc1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.61
TSHR P16473 2/20 0.61
CYP3A4 P08684 1/20 0.61
PTGS2 P35354 2/20 0.59
GAA P10253 11/20 0.55
ALDH1A1 P00352 6/20 0.53
KDM4E B2RXH2 2/20 0.53
MAPT P10636 2/20 0.52
GFER P55789 1/20 0.52
F2 P00734 1/20 0.52
CTSD P07339 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
CRHR1 P34998 1/20 0.47
TP53 P04637 1/20 0.46
EPHX1 P07099 1/20 0.46
EPHX2 P34913 1/20 0.46
CDK9 P50750 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
ALOX12 P18054 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22856571 1.00 ALOX5 (0.61) ALOX5TSHRCYP3A4PTGS2GAA
Phenicarbazide SCHEMBL27711804 0.98 ALOX5 (0.59) ALOX5TSHRCYP3A4PTGS2GAA
SCHEMBL5075214 0.87 PEPD (0.52) ALOX5TSHRCYP3A4PTGS2GAA
SCHEMBL10594245 0.87 PTPN1 (0.50) ALOX5TSHRCYP3A4PTGS2GAA
SCHEMBL9800314 0.86 ALOX5 (0.52) ALOX5TSHRCYP3A4PTGS2GAA
Phenicarbazide SCHEMBL8993011 0.84 ALOX5 (0.46) ALOX5TSHRCYP3A4PTGS2GAA
Hydrazobenzene SCHEMBL10946311 0.82 ALDH1A1 (0.67) ALOX5TSHRCYP3A4PTGS2GAA
SCHEMBL1520818 0.82 ALDH1A1 (0.60) ALOX5TSHRCYP3A4PTGS2GAA
SCHEMBL9179118 0.81 PEPD (0.64) ALOX5TSHRCYP3A4PTGS2GAA
SCHEMBL13434772 0.80 ALDH1A1 (0.69) ALOX5TSHRCYP3A4PTGS2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3573457-B1 PROCESS FOR COOLING A BIOLOGICAL MATERIAL AND THE STORAGE THEREOF GENIALIS (FR) 2025-12-10 EP claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
CN-118388904-B Low-smoke-release and incombustible perfluororubber foam composition, foam and preparation method thereof 上海芯密科技股份有限公司 2025-01-24 CN claimed
CN-118993845-A Method for rapidly reducing secondary alcohol carbonyl value 武汉希音新材料科技有限公司 2024-11-22 CN claimed
WO-2024130044-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) LUMINOUS MIND INC. (US) 2024-06-20 WO claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
CN-118027894-A Adhesive, negative electrode slurry and lithium ion battery 深圳好电科技有限公司 2024-05-14 CN claimed
CN-114717841-B Tear-resistant radiation-proof fabric and preparation method thereof 苏州西铁牛电子商务有限公司 2024-04-26 CN claimed
EP-0140886-B1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS Crystal Diagnostic Systems, Inc. (US) 1988-09-07 EP claimed
EP-0113609-B1 HEAT PROCESSABLE RECORDING ELEMENT AND DYE-FORMING PROCESSING SOLUTION FOR A PHOTOGRAPHIC SILVER HALIDE ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-06-08 EP claimed
EP-0062853-B1 PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-HYDROXY-1,2,4-TRIAZOLES HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-06 EP claimed
EP-0140886-A4 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-09-02 EP claimed
EP-0140886-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-05-15 EP claimed
WO-1984004165-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS LITTLE INC A (US) 1984-10-25 WO claimed
EP-0113609-A2 Heat processable recording element and dye-forming processing solution for a photographic silver halide element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-07-18 EP claimed
US-4426441-A PHOTOTHERMOGRAPHY EASTMAN KODAK COMPANY (US) 1984-01-17 US claimed
US-4380587-A Film badge for determining carbonyl compounds ARTHUR D. LITTLE, INC. (US) 1983-04-19 US claimed
EP-0062853-A2 Process for the preparation of substituted 3-hydroxy-1,2,4-triazoles HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A ALOX5 1054/4885TSHR 2503/4885CYP3A4 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.