Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940614 | 0.83 | ALDH1A1 (0.51) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL19002709 | 0.82 | SMN1; SMN2 (0.67) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| Acetyl Sumiki'S Acid SCHEMBL168107 | 0.81 | NPC1 (0.58) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22856758 | 0.81 | NPC1 (0.54) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2541634 | 0.80 | ALDH1A1 (0.60) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15926026 | 0.80 | ALDH1A1 (0.49) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28244873 | 0.80 | ALDH1A1 (0.49) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14062281 | 0.79 | SMN1; SMN2 (0.48) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12648508 | 0.78 | NPC1 (0.55) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13451413 | 0.78 | ALDH1A1 (0.62) | HTTNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882032-B2 | Furan-2,5-dicarboxylic acid purge process | EASTMAN CHEMICAL COMPANY (US) | 2021-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882032-B2 | Furan-2,5-dicarboxylic acid purge process | DDC, PCCA, DPYD | HTT 3782/4885NPC1 4659/4885RAB9A 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.