SCHEMBL19002709

SCHEMBL19002709

COC(=O)c1ccc(COC(C)=O)o1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.67
HPGD P15428 2/20 0.67
HTT P42858 1/20 0.67
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
HSP90AA1 P07900 1/20 0.61
KMT2A Q03164 3/20 0.59
LMNA P02545 3/20 0.59
MEN1 O00255 2/20 0.59
ALDH1A1 P00352 3/20 0.56
NPSR1 Q6W5P4 1/20 0.56
MAPK1 P28482 1/20 0.54
TSHR P16473 1/20 0.54
ABL1 P00519 1/20 0.53
GAA P10253 1/20 0.53
RIN1 Q13671 1/20 0.53
MAPT P10636 2/20 0.52
POLB P06746 1/20 0.52
KDM4E B2RXH2 1/20 0.52
HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7498200 0.85 L3MBTL1 (0.59) SMN1; SMN2HPGDHTTNPC1RAB9A
SCHEMBL6441147 0.84 HTT (0.73) SMN1; SMN2HPGDHTTNPC1RAB9A
SCHEMBL19940614 0.84 ALDH1A1 (0.51) SMN1; SMN2HPGDHTTNPC1RAB9A
SCHEMBL21594659 0.84 SMN1; SMN2 (0.63) SMN1; SMN2HPGDHTTNPC1RAB9A
SCHEMBL18997822 0.84 SMN1; SMN2 (0.63) SMN1; SMN2HPGDHTTNPC1RAB9A
SCHEMBL23270942 0.83 SMN1; SMN2 (0.50) SMN1; SMN2HPGDHTTNPC1RAB9A
Acetyl Sumiki'S Acid SCHEMBL168107 0.83 NPC1 (0.58) SMN1; SMN2NPC1RAB9AHSP90AA1KMT2A
SCHEMBL21594673 0.83 SMN1; SMN2 (0.48) SMN1; SMN2HPGDHTTNPC1RAB9A
SCHEMBL21594674 0.83 SMN1; SMN2 (0.48) SMN1; SMN2HPGDHTTNPC1RAB9A
SCHEMBL22856757 0.82 HTT (0.47) SMN1; SMN2HPGDHTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638888-B Oxidation process for the production of 5- (alkoxycarbonyl) furan-2-carboxylic Acid (ACFC) 伊士曼化工公司 2024-04-02 CN claimed
EP-3810584-A1 AN OXIDATION PROCESS TO PRODUCE 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS(ACFC) Eastman Chemical Company (US) 2021-04-28 EP claimed
CN-112638888-A Oxidation process for the production of 5- (alkoxycarbonyl) furan-2-carboxylic Acid (ACFC) 伊士曼化工公司 2021-04-09 CN claimed
US-10941245-B2 Oxidation process to produce 5-(alkoxycarbonyl)furan-2-carboxylic acids (ACFC) EASTMAN CHEMICAL COMPANY (US) 2021-03-09 US claimed
US-10544118-B2 Oxidation process to produce 5 methyl 5-methylfuran-2-carboxylate (MMFC) EASTMAN CHEMICAL COMPANY (US) 2020-01-28 US claimed
US-20250223272-A1 COOLING PROCESSES TO PRODUCE ACFC WITH INCREASED CRYSTAL SIZE WITH PURGE EASTMAN CHEMICAL COMPANY (US) 2025-07-10 US disclosed
EP-4025567-B1 EFFICIENT PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)-FURAN-2-CARBOXYLIC ACIDS EASTMAN CHEM CO (US) 2025-04-23 EP disclosed
EP-4508041-A1 COOLING PROCESSES TO PRODUCE ACFC WITH INCREASED CRYSTAL SIZE WITH PURGE Eastman Chemical Company (US) 2025-02-19 EP disclosed
US-20250026729-A1 INTEGRATED PROCESS FOR 5-(METHOXYCARBONYL)FURAN-2-CARBOXYLIC ACID (MCFC) EASTMAN CHEMICAL COMPANY (US) 2025-01-23 US disclosed
US-20240317698-A1 MOTHER LIQUOR COMPOSITION GENERATED IN MCFC PROCESS EASTMAN CHEMICAL COMPANY (US) 2024-09-26 US disclosed
US-20240270708-A1 PURGE PROCESS FOR 5-(ALKOXYCARBONYL)FURAN-2-CARBOYLIC ACID (ACFC) EASTMAN CHEMICAL COMPANY (US) 2024-08-15 US disclosed
CN-114364662-B Efficient process for producing 5- (alkoxycarbonyl) -furan-2-carboxylic acid 伊士曼化工公司 2024-07-12 CN disclosed
US-10941245-B2 Oxidation process to produce 5-(alkoxycarbonyl)furan-2-carboxylic acids (ACFC) EASTMAN CHEMICAL COMPANY (US) 2021-03-09 US disclosed
US-10941245-B2 Oxidation process to produce 5-(alkoxycarbonyl)furan-2-carboxylic acids (ACFC) EASTMAN CHEMICAL COMPANY (US) 2021-03-09 US disclosed
US-10544118-B2 Oxidation process to produce 5 methyl 5-methylfuran-2-carboxylate (MMFC) EASTMAN CHEMICAL COMPANY (US) 2020-01-28 US disclosed
US-10544118-B2 Oxidation process to produce 5 methyl 5-methylfuran-2-carboxylate (MMFC) EASTMAN CHEMICAL COMPANY (US) 2020-01-28 US disclosed
US-20190389846-A1 PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS AND COMPOSITIONS CONTAINING SAME EASTMAN CHEMICAL COMPANY (US) 2019-12-26 US disclosed
US-20190389846-A1 PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS AND COMPOSITIONS CONTAINING SAME EASTMAN CHEMICAL COMPANY (US) 2019-12-26 US disclosed
WO-2017112777-A1 COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE SHY Therapeutics LLC (US) 2017-06-29 WO disclosed
US-20170174699-A1 COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE SHY Therapeutics LLC 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941245-B2 Oxidation process to produce 5-(alkoxycarbonyl)furan-2-carboxylic acids (ACFC) MCCC2, ACSL5, ACACB SMN1; SMN2 3106/4885HPGD 872/4885HTT 4744/4885
US-20250223272-A1 COOLING PROCESSES TO PRODUCE ACFC WITH INCREASED CRYSTAL SIZE WITH PURGE ACACA, ADCY10, MCCC2 SMN1; SMN2 2528/4885HPGD 2475/4885HTT 4250/4885
US-20240317698-A1 MOTHER LIQUOR COMPOSITION GENERATED IN MCFC PROCESS MCCC2, MLEC, ACSL5 SMN1; SMN2 2033/4885HPGD 1446/4885HTT 4779/4885
US-20190389846-A1 PROCESS FOR PRODUCING 5-(ALKOXYCARBONYL)FURAN-2-CARBOXYLIC ACIDS AND COMPOSITIONS CONTAINING SAME CA5B, ACSL5, CA5A SMN1; SMN2 1099/4885HPGD 1360/4885HTT 4198/4885
US-10544118-B2 Oxidation process to produce 5 methyl 5-methylfuran-2-carboxylate (MMFC) MCCC2, ACSL5, ACACB SMN1; SMN2 3053/4885HPGD 766/4885HTT 4790/4885
US-20240270708-A1 PURGE PROCESS FOR 5-(ALKOXYCARBONYL)FURAN-2-CARBOYLIC ACID (ACFC) MCCC2, ACACB, ACACA SMN1; SMN2 3140/4885HPGD 967/4885HTT 4612/4885
US-20250026729-A1 INTEGRATED PROCESS FOR 5-(METHOXYCARBONYL)FURAN-2-CARBOXYLIC ACID (MCFC) MCCC2, RFC5, ACSL5 SMN1; SMN2 2055/4885HPGD 2973/4885HTT 3549/4885
US-20170174699-A1 COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE MAPK6, MAP3K6, MAPK4 SMN1; SMN2 4331/4885HPGD 365/4885HTT 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.