Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25634095 | 0.94 | PDK2 (0.43) | PDK2CA12CA1CA2CA7 | |
| SCHEMBL30421629 | 0.82 | ALK (0.44) | PDK2RARARARBRARG | |
| SCHEMBL22859400 | 0.82 | ALK (0.44) | PDK2RARARARBRARG | |
| SCHEMBL25199664 | 0.78 | CA12 (0.48) | PDK2CA12CA1CA2CA7 | |
| SCHEMBL10045392 | 0.76 | TSHR (0.54) | PDK2RAB9AALDH1A1NPC1MAPK1 | |
| SCHEMBL22859111 | 0.74 | MAPT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30422168 | 0.74 | MAPT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12154187 | 0.73 | RARA (0.52) | PDK2CA12CA1CA2CA7 | |
| SCHEMBL22859291 | 0.72 | CA12 (0.42) | PDK2CA12CA1CA2CA7 | |
| SCHEMBL19935930 | 0.72 | ALDH1A1 (0.40) | PDK2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230194165-A1 | RADIOFREQUENCY HEATING OF WOOD USING A THREE-ELECTRODE SYSTEM HAVING A WINGED CENTRAL ELECTRODE | RF KILN TECH LIMITED (CA) | 2023-06-22 | — | — | US | disclosed |
| US-11666637-B2 | Insulin-loaded metal-organic frameworks | NORTHWESTERN UNIVERSITY (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210000924-A1 | INSULIN-LOADED METAL-ORGANIC FRAMEWORKS | NORTHWESTERN UNIVERSITY | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11666637-B2 | Insulin-loaded metal-organic frameworks | IAPP, IGFBP4, IGFBP1 | PDK2 1431/4885CA12 800/4885CA1 1198/4885 |
| US-20210000924-A1 | INSULIN-LOADED METAL-ORGANIC FRAMEWORKS | IAPP, IGFBP4, IGFBP1 | PDK2 1431/4885CA12 800/4885CA1 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.