Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864003 | 0.86 | KDM4E (0.52) | KDM4ESLC18A3SIGMAR1DRD2 | |
| SCHEMBL14760859 | 0.74 | SIGMAR1 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL14760858 | 0.74 | SIGMAR1 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL14761087 | 0.74 | SIGMAR1 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL22863936 | 0.73 | S1PR5 (0.70) | KDM4ESLC18A3SIGMAR1 | |
| SCHEMBL23989918 | 0.71 | FABP7 (0.48) | — | |
| SCHEMBL26630741 | 0.71 | FABP7 (0.48) | — | |
| SCHEMBL28043174 | 0.70 | KDM4E (0.49) | KDM4ESLC18A3SIGMAR1DRD2 | |
| SCHEMBL22488321 | 0.70 | ALDH1A1 (0.57) | KDM4ESLC18A3SIGMAR1 | |
| SCHEMBL22488317 | 0.70 | ALDH1A1 (0.57) | KDM4ESLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003398-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-01-07 | — | — | WO | disclosed |