Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883053 | 0.72 | HTR2C (0.46) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| SCHEMBL13372443 | 0.72 | HTR2C (0.46) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| SCHEMBL5749290 | 0.72 | HTR2C (0.46) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| SCHEMBL548964 | 0.72 | HTR2C (0.46) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| SCHEMBL31378005 | 0.72 | PAX8 (0.33) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| SCHEMBL30417082 | 0.72 | CHRNB4 (0.39) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30259584 | 0.71 | HTR2C (0.44) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL13387451 | 0.71 | HTR2C (0.44) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| SCHEMBL13323694 | 0.68 | CHRNB4 (0.37) | CHRNB4CHRNA3PAX8MEN1KMT2A | |
| SCHEMBL793625 | 0.68 | CHRNB4 (0.37) | CHRNB4CHRNA3PAX8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000935-A1 | HPK1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2021-01-07 | — | — | WO | disclosed |