Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27837408 | 0.79 | CHRNB4 (0.35) | PAX8CHRNB4CHRNA3MEN1KMT2A | |
| SCHEMBL19158834 | 0.74 | POLB (0.47) | PAX8MEN1KMT2AKCNH2EPHX2 | |
| SCHEMBL22864426 | 0.72 | CHRNB4 (0.33) | PAX8CHRNB4CHRNA3MEN1KMT2A | |
| SCHEMBL11049443 | 0.71 | KCNH2 (0.33) | PAX8CHRNB4CHRNA3KCNH2EPHX2 | |
| SCHEMBL3042387 | 0.70 | MTNR1A (0.40) | PAX8KCNH2EPHX2 | |
| SCHEMBL27723361 | 0.70 | PAX8 (0.36) | PAX8KCNH2 | |
| SCHEMBL9036022 | 0.69 | EPHX2 (0.40) | PAX8KCNH2EPHX2 | |
| SCHEMBL27739880 | 0.69 | LMNA (0.39) | PAX8KCNH2EPHX2 | |
| SCHEMBL5749290 | 0.69 | HTR2C (0.46) | PAX8CHRNB4CHRNA3MEN1KMT2A | |
| SCHEMBL13372443 | 0.69 | HTR2C (0.46) | PAX8CHRNB4CHRNA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-B | HPK1 inhibitors and uses thereof | 锐格药业公司 | 2025-02-11 | — | — | CN | disclosed |