Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507086 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAOBAOC3KIF11GRM4 | |
| SCHEMBL3368887 | 0.79 | WDR5 (0.66) | WDR5MAOBIDO1 | |
| SCHEMBL20019078 | 0.78 | MAOB (0.51) | WDR5MAOBPPARA | |
| SCHEMBL11537941 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAOBAOC3KIF11GRM4 | |
| SCHEMBL13629002 | 0.76 | ALDH1A1 (0.49) | WDR5ALDH1A1MAOBAOC3GRM4 | |
| SCHEMBL2111994 | 0.76 | PPARD (0.68) | ALDH1A1MAOBAOC3GRM4PPARD | |
| Hydrochloric Acid SCHEMBL4433395 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAOBAOC3GRM4PPARD | |
| SCHEMBL21360612 | 0.75 | WDR5 (0.66) | WDR5 | |
| SCHEMBL9194768 | 0.75 | WDR5 (1.00) | WDR5ALDH1A1 | |
| SCHEMBL4100035 | 0.75 | WDR5 (0.66) | WDR5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003295-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |