Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MDH1 | P40925 | 1/20 | 0.49 |
| ▸ | MDH2 | P40926 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506137 | 0.84 | MEN1 (0.58) | ALDH1A1POLBBLMTDP1 | |
| SCHEMBL2111994 | 0.83 | PPARD (0.68) | ALDH1A1MAOBAOC3GRM4PPARD | |
| SCHEMBL1116911 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAOBAOC3KIF11PPARA | |
| SCHEMBL22868083 | 0.81 | WDR5 (0.59) | ALDH1A1MAOBAOC3KIF11GRM4 | |
| SCHEMBL12611856 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAOBAOC3KIF11GRM4 | |
| SCHEMBL11537941 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAOBAOC3KIF11GRM4 | |
| SCHEMBL2171542 | 0.81 | MAOB (0.57) | ALDH1A1MAOBAOC3SMN1; SMN2PDK2 | |
| SCHEMBL6153892 | 0.81 | SMN1; SMN2 (0.71) | ALDH1A1MAOBAOC3SMN1; SMN2POLB | |
| SCHEMBL11525116 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAOBAOC3GRM4PPARD | |
| SCHEMBL10931313 | 0.81 | KDM4E (0.49) | ALDH1A1MAOBAOC3PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239937-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-112189008-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-106749076-B | Application of o-hydroxyphenyl azole derivative as organic blue light material | 四川大学 | 2020-09-11 | — | — | CN | disclosed |
| WO-2005035526-A1 | BICYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LTD. (GB) | 2005-04-21 | — | — | WO | disclosed |
| US-4133808-A | 4-(Formylthio)azetidinones and ozonization process therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4048157-A | 4(Formylthio)-azetidin-2-ones and ozonization process therefor | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |