Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | MDH1 | P40925 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4433395 | 0.98 | ALDH1A1 (0.48) | ALDH1A1MAOBAOC3TRPM8CYP1A1 | |
| SCHEMBL5279675 | 0.81 | GAA (0.60) | ALDH1A1MAOBTRPM8CYP1A1CYP1B1 | |
| SCHEMBL11077869 | 0.78 | ALOX15 (0.48) | ALDH1A1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23605965 | 0.77 | GAA (0.56) | ALDH1A1MAOBTRPM8CYP1A1CYP1B1 | |
| Hydrochloric Acid SCHEMBL2826316 | 0.77 | PMP22 (0.47) | ALDH1A1LMNAMAPTL3MBTL1WDR5 | |
| SCHEMBL8237725 | 0.77 | NQO1 (0.64) | ALDH1A1MAOBAOC3CYP1A1CYP1B1 | |
| Hydrochloric Acid SCHEMBL2983751 | 0.76 | ALOX15 (0.47) | ALDH1A1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22868083 | 0.76 | WDR5 (0.59) | ALDH1A1MAOBAOC3PPARDGRM4 | |
| SCHEMBL13603746 | 0.73 | PPARD (0.54) | ALDH1A1MAOBAOC3TRPM8CYP1A1 | |
| Hydrochloric Acid SCHEMBL11539234 | 0.73 | PMP22 (0.43) | MAOBSMN1; SMN2LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612211-B2 | Benzimidazole TRPV1 inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-11-03 | — | — | US | disclosed |
| US-20080146637-A1 | BENZIMIDAZOLE TRPV1 INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146637-A1 | BENZIMIDAZOLE TRPV1 INHIBITORS | TRPV1, TRPV2, TRPA1 | ALDH1A1 747/4885MAOB 1031/4885AOC3 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.