SCHEMBL228690

SCHEMBL228690

CNc1ccc(Cl)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10343601 0.97 ALDH1A1 (0.48)
SCHEMBL6161280 0.92 KIF11 (0.54)
SCHEMBL1108591 0.85 MAOA (0.52)
SCHEMBL29113884 0.83 MAPT (0.54)
SCHEMBL153943 0.83 TSHR (0.67)
Pyridine SCHEMBL28758817 0.82 TSHR (0.46)
SCHEMBL28653668 0.82 ALDH1A1 (0.42)
SCHEMBL874104 0.82 SRD5A2 (0.57)
SCHEMBL28495327 0.80
SCHEMBL22198268 0.80 GRIN2D (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391829-B2 Polyarylene sulfide resin composition, method of preparing polyarylene sulfide resin composition, and heat insulating material manufactured using polyarylene sulfide resin composition LG CHEM, LTD. (KR) 2025-08-19 US claimed
CN-116622081-B Non-noble metal cage MOFs catalyst for producing N-benzamide and preparation method and application thereof 内蒙古大学 2025-06-24 CN claimed
CN-115322132-B N-substituted indole compound and synthesis method thereof 陕西科技大学 2024-05-28 CN claimed
CN-116178258-B N-methylaniline quinoline compound and synthetic method and application thereof 中国医学科学院北京协和医院 2023-11-21 CN claimed
CN-111302951-B N-deuterium methyl amine compound and preparation method thereof 深圳大学 2023-10-17 CN claimed
CN-116622081-A Non-noble metal cage MOFs catalyst for producing N-benzamide and preparation method and application thereof 内蒙古大学 2023-08-22 CN claimed
CN-116178258-A N-methylaniline quinoline compound and synthetic method and application thereof 中国医学科学院北京协和医院 2023-05-30 CN claimed
CN-112209847-B Method for preparing amide compound under catalysis of ionic liquid in high-pressure environment 烟台大学 2022-12-23 CN claimed
CN-115322727-A High-strength double-component polyurethane structural adhesive and preparation method thereof 福建省昌德胶业科技有限公司 2022-11-11 CN claimed
CN-115322132-A N-substituted indole compound and synthetic method thereof 陕西科技大学 2022-11-11 CN claimed
EP-0208404-B1 BENZOTHIAZINE DIOXIDE DERIVATIVES PFIZER INC. (US) 1990-08-29 EP claimed
EP-0378615-A1 NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES COMPETITIVE TECHNOLOGIES INC. (US) 1990-07-25 EP claimed
WO-1989011486-A1 NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES UNIVERSITY PATENTS, INC. (US) 1989-11-30 WO claimed
EP-0208404-A2 Benzothiazine dioxide derivatives PFIZER INC. (US) 1987-01-14 EP claimed
US-4623486-A [4-substituted benzoyloxy]-N-substituted-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity PFIZER INC. (US) 1986-11-18 US claimed
EP-0087000-B1 N-OXALYL DERIVATIVES OF N-METHYL CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1985-11-13 EP claimed
US-4297158-A ACTIVATION OF PEROXY CATALYST BY A CARBO-TERT-AMINE; MIXTURE OF POLYURETHANE OR ELASTOMER AND ACRYLIC MONOMERS PRATT & LAMBERT, INC. (US) 1981-10-27 US claimed
EP-0021598-A1 A kinetic method for directly determining total bilirubin BECKMAN INSTRUMENTS, INC. (US) 1981-01-07 EP claimed
US-4212921-A TERTIARY AMINES, PEROXY CATALYST, UNSATURATED MONOMER PRATT & LAMBERT, INC. (US) 1980-07-15 US claimed
US-4155950-A CURING, PEROXY CATALYST PRATT & LAMBERT, INC. (US) 1979-05-22 US claimed