Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 6/20 | 0.73 |
| ▸ | AMD1 | P17707 | 2/20 | 0.73 |
| ▸ | NNMT | P40261 | 5/20 | 0.66 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.65 |
| ▸ | PCMT1 | P22061 | 3/20 | 0.65 |
| ▸ | NSD2 | O96028 | 3/20 | 0.65 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.65 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.65 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.65 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.65 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.65 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.65 |
| ▸ | INMT | O95050 | 2/20 | 0.65 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.65 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.65 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.65 |
| ▸ | RNMT | O43148 | 1/20 | 0.65 |
| ▸ | TPMT | P51580 | 1/20 | 0.65 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.65 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287296 | 1.00 | CARM1 (0.73) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL2287316 | 1.00 | CARM1 (0.73) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL12378915 | 1.00 | CARM1 (0.73) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL31425158 | 0.93 | CARM1 (0.70) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL2287080 | 0.88 | CARM1 (0.81) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL30930805 | 0.88 | CARM1 (0.78) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL2287090 | 0.88 | CARM1 (0.81) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL2287096 | 0.88 | CARM1 (0.81) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL30965845 | 0.88 | CARM1 (0.78) | CARM1AMD1NNMTDOT1LPCMT1 | |
| SCHEMBL2284764 | 0.87 | CARM1 (0.79) | CARM1AMD1NNMTDOT1LPCMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008007-B2 | S-adenosyl-L-methionine analogs with extended activated groups for transfer by methyltransferases | RWTH AACHEN (DE) | 2011-08-30 | — | — | US | disclosed |
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-1874790-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH Aachen (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108678-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | BHMT2, MSRB3, PRMT3 | CARM1 35/4885AMD1 20/4885NNMT 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.